In the Romantic period of literature, nature was often associated with isolation in a positive way. Throughout the novel, Frankenstein: The Modern Prometheus, by Mary Shelley, there is a strong symbolic relationship between solitude and nature. However, Shelley uses the relationship to show the negativity of being alone. The relationship between nature and solitude is shown through three characters in the story: Victor Frankenstein, his creature, and Robert Walton. In moments when the characters are alone and need company, they feel depressed, confused and angry; they don't think clearly and, as a result, make bad decisions. They seek refuge in nature and try to use its beauty to find answers and fill their void of friendship. However, none of the characters ever overcome their bouts of loneliness because they never find true solace in nature. Victor Frankenstein states: "No human being could have had a happier childhood than mine"; (Shelley, 19 years old). His early life was filled with love and nurturing from his parents, his beautiful and adored companion Elizabeth and his best friend Henry Clerval. However, after leaving his home to continue his education in Ingolstadt, he observes: "I, who had always been surrounded by amiable companions, continually engaged in the attempt to give mutual pleasure, was now alone"; (Shelley, 25 years old). Frankenstein no longer feels all the happiness he once felt when he was united with his family and friends. He alienates himself from others because he thinks he is “totally unfit for the company of strangers”; (Shelley, 25). When Frankenstein is in Ingolstadt, “he has a void in his soul”; so deep that it subverts Nature to fill it (qtd. in Renfroe, 2). He conceives: “A new species would bless me as its creator and source; many happy and excellent natures owe their existence to me"; (Shelley, 32 years old). Frankenstein decides to create a creature, to challenge the powers of nature and God: a bad decision that ruins the rest of his life. When Victor finally succeeds in his attempt to possess Nature, “horror and disgust”; fill his heart by seeing his new creation (qtd. in Renfroe, 2). He sought companionship by capturing Nature and creating someone who would honor him for giving him life; but this failed and he sealed his fate to the wrath of his creation. When Victor Frankenstein is once again separated from his beloved family and friends, this time with their deaths, he feels the pangs of isolation..