In recent decades, nanotechnology has been considered an applied technology. This technology produces and controls materials, tools and new molecular-atomic sized systems created by the combination of physical, chemical and biological sciences. The new Nano size materials have new advantages and characteristics that they did not have before. Nanotechnology has different types of operations, such as: food, drugs, medical diagnosis, biotechnology, electronics and computers, communication, transportation, energy, security, health and environment, aerospace and so on. Unique characteristics of each nanomartial size, shape, biocompatibility, solubility are important factors in biological efficiency.HistoryA) Medical development and appearance of nanomedicineNano Medical is the application of nanoscale approaches, theories, devices and structures in order to identify, prevent or cure diseases through sensing, repair damaged tissues at the biomolecular level. The main focus of nanomedicine is pathological and therapeutic structures on the molecular and minute scales. According to research by Majo et al, the main application fields of nanomedicine that present cyber challenges include: drug delivery, implantable devices, diagnostics, prevention and therapy. Nanoparticles can be used as carriers of drugs or certain organic molecules. Nano delivery is the transfer of nanoscale objects into the body and their penetration into cells. One of the obstacles to progress in this area is the high cost of drug development, which varies from 3 thousand to 11.5 million dollars. Many nanoscale implantable devices, such as nanorobots, can be designed to monitor diseases. For example, nanoscale devices can be attached to the patient and...... center of paper ......d quantify tumors in the near-infrared region. 2009, Elsevier. P. 216-224.22. Lanza, GM, et al., Targeted delivery of antiproliferative drugs to vascular smooth muscle cells with implications of a nanoparticle magnetic resonance imaging contrast agent for rational restenosis therapy. 2002, Am Cuore Assoc. P. 2842-2847.23. Popovtzer, R., et al., Targeted gold nanoparticles enable molecular CT imaging of cancer. 2008, ACS Publications. P. 4593-4596.24. Chaimovich, A. and M. S. Shell, Coarse-grained errors and numerical optimization using a relative entropy framework. P. 094112.25. Xia, P. 671-675.26. Shaw, S.Y., et al., Perturbation profiles of the biological activity of nanomaterials. 2008, National Acad Sciences. P. 7387.