IndexAbstract: :: : :SynonymBiological sourceDescriptionDescriptionCultivation detailsPhytochemical analysis of plant partsAsh value of plant parts:Therapeutic properties of Pithecellobium DulceAnti-inflammatory activityAntibacterial-activityAntioxidant-activityAntidiabetic-activityAntimicrobial activityActivity anticonvulsantsCardioprotective activityAntidiarrheal activityLarvicidal and ovicidal activityAntiulcerogenic activityAntifungal activityConclusionAbstract: :: : :The phytochemical screening of plants revealed the presence of different chemical substances together consisting of alkaloids, tannins, flavonoids, steroids, glycosides, saponins. Numerous plant extracts and phytochemicals exhibit free radical-scavenging antioxidant properties. Plant secondary metabolites function as an unconscious process against predation by numerous microorganisms, insects and herbivores. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Plant products have been part of phytomedicines since ancient times. These can be derived from any element of the plant such as bark, leaves, flowers, roots, fruits, seeds. Any part of the plant could contain an active compound. Knowledge of the chemical constituents of plants is fascinating because such data will be important for the synthesis of complex chemicals. Such phytochemical screening of assorted plants is reported by several analysts. In the present work, qualitative and quantitative phytochemical analysis was carried out within the leaf, fruit and fruit of Pithocellobium dulce. The Pithecellobium dulce plant has many uses and has a versatile role in the ancient healing system. There are many ongoing studies on the effectiveness of the whole plant or its components for treating various diseases and disorders. The active compound of the plant includes flavonoids, sterols, tannins, tri-terpenoids etc. Health-promoting properties due to the presence of proteins, carbohydrates, steroids etc. and disease-preventing properties such as antifungal, antiviral, bactericidal, antidiabetic, diastolic, diuretic, anthelmintic effects, antipyretic, anti-inflammatory, hypoglycemic and sedative activity which has been investigated and verified by research. The assorted properties of the tree (P.dulce) therapeutic properties are mentioned in this report. Synonym Inga dulcis (Roxb.) willd, manila tamarind, Khoi babla (Bengali), Dekhani babul (Bengali), madras thorn, Quamochil, Bakhoi ambli (Gujrati), Huamuche (Japan) etc. Organic source Obtained from ripe fruits, leaves and from the pod of Pithocellobium dulce which belongs to the Fabaceae family. Description It is a small to medium sized tree with a white, straight spine. The leaves are bipinnate in nature and each pinnate has a pair of leaflets; the flyers are partial; dense; long and obvate. The size of the leaflets is approximately 2.5 cm long and is subsessile. The flowers are tiny, white in color and have small ball-shaped heads. The diameter of the flower is 1 cm. The pods are distorted, are 10-20 cm long, fleshy, turgid and become reddish in color when ripe. The pods are edible and consist of a fleshy, sweetish, acidic pulp. It can be eaten plain or raw or processed into a lemonade-like drink. Oil can be extracted from the seeds which is used in cooking or for the preparation of soaps. Cultivation Details The tree grows at low and medium altitudes in humid regions as well as in the dry region of the tropics. This tree grows in a region where the average temperature is between 18 and 27.9 °C. Requires drained soil in one locationsunny and can easily grow plants. It can also grow in heavy clay soil. This tree can grow even in poor soil. It starts flowering when the tree reaches 1-2 meters in height. In 40 years the tree can reach 12-15 meters in height. The tree can reach 10 meters in height. meters in 5-6 years if the soil condition is favourable. The tree straightens vigorously and produces root suckers if the roots are injured. Once planted in the field, it does not require any type of treatment except occasional pruning. This species interacts with some soil bacteria, these bacteria form nodules on the roots and fix atmospheric nitrogen. This tree uses nitrogen to grow but nitrogen used by other plants that are close to this tree. The tree can tolerate a pH up to 8.3.Phytochemical analysis of plant partsPhytochemical screening of plants revealed the presence of various chemical substances including alkaloids, tannins, flavonoids, steroids, glycosides, saponins. Several plant extracts and phytochemicals exhibit inhibitory atom-scavenging properties. Plant secondary metabolites function in an unconscious process against predation by numerous microorganisms, insects and herbivores. Plant products have always been part of phytomedicines. These can be derived from any element of the plant such as bark, leaves, flowers, roots, fruits, seeds. Any part of the plant could contain an active compound. Knowledge of the chemical constituents of plants is fascinating because such data will be important for the synthesis of complex chemicals. Such phytochemical screening of assorted plants is reported by several analysts. As part of the gift work, a qualitative and quantitative phytochemical analysis of the leaves, fruits and fruit of Pithocellobium dulce was carried out. Value of ash of plant parts: Total ash is the residue left after incineration. Acid-insoluble ash is that portion of the total ash that is insoluble in dilute hydrochloric acid. Ash values are useful in determining the quality and purity of the raw drug in powder form. % Total Ash = Weight of Total Ash × 100 Weight of Raw Drug % Acid Insoluble Ash Value = Weight of Acid Insoluble Ash × 100 Weight of the crude drug Parts of the plant Ash valueFruit (100 g) 0.6 gWhole fruit with peel and seeds (100 g) 0.2 gSeeds (100 g) 2.6 gFoliage (100 g) 15.34 gTherapeutic properties of Pithecellobium DulceActivities Anti-inflammatoryAnti-inflammatory refers to the property of a substance or treatment that reduces inflammation or swelling. The ethanolic extract of the tree showed the presence of secondary metabolites similar to alkaloids, flavonoids, glycosides, phenols, steroids, tannins, terpenoids and saponins showed an increase in the response proportion of inhibition of denaturation of macromolecules and stabilization of membrane of HRBCs when placed next to the drug quality Aspirin by approximately 62.80 and 59.25% respectively. The ethanolic and binary compound leaf extracts of P. dulce have been studied for its medicinal activity victimization carrageenan-induced paw swelling in rats. Each extract showed significant medicinal activity by reducing paw volume at the dose level tested. The binary compound extract showed much activity compared to the alcohol extract which was a valuable non-steroidal anti-inflammatory, a typical anti-inflammatory drug. Antibacterial activity Ethyl acetate from the peel of the Camachile fruit was effective against S. epidermis, E. coli, K. pneumonia, S. aureus, E. faecalis, P. aeruginosa and P. putida, while the methanolic extract was active against K. pneumonia, S.aureus and P. putisda. The binary compound extract was effective exclusively against K. aureus respiratory disease, while the rock oil ether extract was active exclusively against P. Putida. The results jointly indicated that peel extracts, especially methanolic extracts, esters, and binary compounds, show the ability to quench the DPPH radical, suggesting that the extracts are smart radical antioxidants. P. dulce pod pulp extract revealed effective repressive activity against gram-positive microorganisms, gram-negative bacilli and microorganisms, and enterobacteria of respiratory diseases. B. subtilis showed a larger clearance diameter than that of alternative Gram-positive organisms. Similarly, the extract showed a larger clearance zone within the Gram-negative organism, K. pneumonia, than that of other Gram-negative organisms. Antioxidant activity Oxidative stress is known as the main cause of the onset and progression of many diseases. Therefore, plants containing secondary metabolites love phenoplastic compounds possess strong inhibitory activity of P. dulce leaf extract ready in numerous solvents (acetone, methanol and water). Its inhibitory activity was evaluated by analysis of phenoplast content, FRAP, DPPH and gas radical scavenging activity analysis. The results showed that the presence of phenoic content (alkaloids, terpenoids, phlobatannins, coumarins, tannins and flavonoids) within the extract, however, a higher content was found in the metonic extract. IC50 prices for FRAP, DPPH, gas radical scavenging tests for dissolving agent (72.17, 13.70, 50.7), alcohol (49.77, 74.89) and aqueous extract were reported ( 91.5, 67.41, 81.80) which authenticate the inhibitory activities and antifungal activity. The alcohol and seventy-dissolving agent extracts of the wood bark and leaves of P. dulce were evaluated for inhibitory activity and the results revealed that the wood bark and leaves of the plant are the numerous sources of total inhibitory activity with an intelligent content of total phenoplasts and flavonoid content. It is also found to be an honest iron. therefore everywhere the plant could be useful in preventing the progression of various oxidative stresses. 14 Antidiabetic activity In this study, on rats treated with alloxan, there was a significant increase in glucose, sterol and glyceride levels. Oral treatment with 200 mg/kg body weight and 400 mg/kg body weight of huamachil bark hydroalcoholic extract considerably reduced glucose, sterol, and glyceride compared to quality glibenclamide. The antidiabetic activity is therefore also due to the presence of phytoconstituents such as sterols, alkaloids, glycosides, saponins, tannins, carbohydrates, proteins, synthetic resin compounds and flavonoids in the alcoholic extract of the bark of P. dulce. Oral administration of P. dulce fruit extract (300 mg/kg body weight/day) to diabetic rats for thirty days considerably reduced the level of glucose, glycosylated Hb, carbamide and creatinine. The altered levels of mood aminotransferase and alkalescent enzyme were normalized after treatment with fruit extract and also determined that the decrease in protein, plasma endocrine and Hb levels in diabetic rats was elevated to the traditional level. The amount of poliose content was improved after treatment with the extract. Therefore, the results of the study demonstrated that the fruit extract is non-toxic and has anti-diabetic nature. Antimicrobial activity The prepared silver nanoparticlesbiologically from the huamachil plant have developed sensitivity against the strains of microorganisms E. coli, S. aureus, P. aeuruginosa and C. albicans showed the best sensitivity among the various concentrations used for the antimicrobial activity of the P. dulce leaf against winds infectious microorganisms. P. dulce leaf extracts were prepared in H2O and organic solvents. Agar well diffusion technique was used to evaluate the antimicrobial activity of leaf extracts against 5 Gram-positive (Bacillus subtilis, E. faecalis, M. luteus, S. aureus and S. epidermidis), seven Gram- negative (Aeromonas hydrophila, A. faecalis, E. aerogenes, E. coli, K. pneumoniae, P. aeruginosa and S. typhimurium) bacterium and eight fungi (A. flavus, A. niger, A. oryzae, A. terreus, A. alternata, Alternaria brasicola, A. solani and A. vitis). The extracts showed variable zones of inhibition (ranging from seven to twenty-seven mm) against most of the microbes tested. Solvent extracts were found to be simpler than liquid extract. The most prone being was E. faecalis which had an inhibition zone of 27 millimeters. Rock bottom MIC values against E. faecalis were obtained, indicating the strain condition for all extracts. The results of the study indicated that P. dulce extracts possess bioactive compounds with antimicrobial properties. Anticonvulsant activity Epilepsy is characterized by the reappearance of seizures related to loss or disturbance of consciousness, typically but not always accompanied by characteristic body movements (convulsions) and invariably correlated with abnormal and excessive discharge of graphic recording. The anticonvulsant pharmacological activity of the crude flavonoid fraction of P. dulce leaf (CFFPD) victimized pentylenetetrazole (PTZ)-coating body and external shock (MES) treatment models in rats, the crude flavonoid fraction showed an important reduction during the period of extension of the hind leg and onset of seizures, the dose in each external shock treatment takes a look at the pentylenetetrazole model. The ethanolic, liquid extract of huamachil leaves has been studied for its anticonvulsant pharmacological activity victimization outside of electroshock (MES)-induced seizures in rats. Each extract showed significant anticonvulsant pharmacological activity by reducing the extension period at the dose level tested. The liquid extract showed results more similar to Dilantin metal, a regular medicine. Cardioprotective Activity The cardioprotective result of grain alcohol and huamachil fruit liquid extract in Isuprel (ISO) iatrogenic organic chemistry and histapathological changes of maltreated rats revealed that ISO-induced rats showed a large increase in activities marker enzymes such as body fluid pyruvate aminopherase (SGOT), body fluid pyruvate aminopherase (SGPT), internal organ marker enzymes such as amino acid phosphokinase (CPK) and nurse dehydrogenase (LDH). Pretreated with liquid and ethanolic extract of P. dulce fruit peel, it completely altered the activity of marker enzymes and therefore organic chemistry parameters in ISO-iatrogenic rats. Liquid extracts of P. dulce fruit and flower reverse iatrogenic damage to internal organs by (ISO) Isuprel. Compared to the quality cardioprotective agent Isoptin, the plant extracts had almost the same effects against heart attack. Antidiarrheal Activity Ethanol and Liquid Extract of Huamachil Leaves for Its Antidiarrheal Activity in the Treatment of Iatrogenic Cathartic Intestinal Dysfunction in Rats Wistar reported that the extracts reduced the frequency and wetness of excretions compared to.
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