Divorce, marital conflict, social isolation, basic trust relationships and problems with their relationships are a big problem with social groups where a patient is not educated and willing to be their support. The patient must be willing to change the people around him and make choices to have strong support. Your support team needs to be able to see the signs of your mood and personality changes. Bipolar mania or depression can come on suddenly, and getting immediate treatment could be the difference between life and death.