The most effective drugs are somatostatin analogues, dopamine agonists and Pegvisomant. Not only that, there is also the possibility of using radiotherapy to bring hormones back to normal, but it takes 5 to 10 years for its full effects to manifest. The other problem is that radiation is known to cause many disabilities and problems in children. Normally doctors would only recommend it as a last resort if surgery or medications don't do it