LSD is a powerful mind-altering substance that can not only change a person's consciousness but also an entire society. He created his own culture, and without it America would not be the same. LSD-25, or d-lysergic acid diethylamide, is a fairly common and extraordinarily potent psychoactive drug. This semi-synthetic hallucinogen was first synthesized in 1938 by Albert Hofman. It is almost always taken orally, in the form of sugar cubes, infused in sweets or more commonly in wipes. It is very potent in low doses and was the famous drug that dramatically changed America in the 1960s. LSD-25 was first synthesized in 1938 from ergotamine, a chemical derived from ergot, a fungus that grows on grains, typically rye. . LSD is not physically addictive, but can be psychologically addictive. This means that if you get used to taking LSD, if you stop taking it there will be a noticeable difference, as if you feel like part of your brain has disappeared. LSD is a very potent drug in terms of how much of the substance is needed to get high. It is very potent at low doses. Below is a graph showing LSD doses per micrograms. Oral LSD Dosages Amount (in micrograms) Threshold 20 ug Mild 25 ug - 75 ug Common 50 ug - 150 ug Strong 150 ug - 400 ug Heavy 400 + ug LSD is most commonly taken in blotter, which is made of paper decorated pad divided into ¼ inch squares, called tabs. A typical pill can contain 30 ug to 100 ug of LSD. Paper swabs are typically made of decorated, perforated absorbent paper and immersed in a dilution of lysergic acid diethylamide. The strength of the dilution can vary greatly depending on the batch and who produced it. LSD is soluble (can dissolve) in water and other… paper, and without it America would not be the same. Bibliography "Lysergic acid diethylamide". Wikipedia. Wikimedia Foundation, November 22, 2013. Web. November 24, 2013. From this source I learned specifically about the medicinal uses of LSD and its potential adverse effects. “How LSD Works.” How things work. Np, nd Web. November 24, 2013. From this source I learned how LSD is produced and how it affects the brain."Erowid LSD (Acid) Vault." Erowid LSD (acid) depot. Np, nd Web. December 01, 2013. From this source I have learned everything I will ever need to know about LSD. “LSD: Penalties for Sale and Possession.” Find a lawyer. Np, nd Web. December 05, 2013Here I learned about the legal punishment of LSD crimes."History of Lysergic Acid Diethylamide." Wikipedia. Wikimedia Foundation, 12 January 2013. Web. 08 December 2013Here I discovered the past of LSD.